PHILA. (1-2) AT GREEN BAY (3-0), Thur., 8:20 p.m. ET
TV: NFL NETWORK LINE: Green Bay -4.5
What you need to know: In Week 3, fumbles by Miles Sanders and Nelson Agholor hurt the Eagles. In fact, those plays led to six Lions points and provided the difference in a surprising home loss for Philadelphia. With the Cowboys looking strong and Giants revived by Daniel Jones’ winning debut, the Eagles must win to keep from falling out of the race early. Green Bay hasn’t started 4-0 since 2015, when it won its first six games before losing four of its next five. That the Packers are unbeaten is testament to their balance, as Aaron Rodgers’ play has not been scintillating. Green Bay boasts the league’s No. 2 scoring defense, and its eight takeaways are best in the league. The pass rush (12 sacks) is getting after it, too. The rush defense, however, ranks 25th.
On the spot: Eagles RB Miles Sanders. Sanders has not proven himself ready for the role of feature back, but the Eagles need him to hold up his end of the bargain in a partnership with Jordan Howard.
Packers QB Aaron Rodgers: An opportunistic defense is arguably most responsible for Green Bay’s fast start, so Rodgers must pick up his game to keep the Packers atop what appears to be the best division.
The pick: Packers 30 Eagles 24 2 of 15
TENNESSEE (1-2) AT ATLANTA (1-2), Sunday, 1 p.m. ET
TV: CBS LINE: Atlanta -3.5
What you need to know: Tennessee had a chance to make a major statement against the Jaguars in Week 3 but flopped, and its dominant season-opening win over Cleveland feels like long ago. As in Week 2, offense was the problem for the Titans, with Marcus Mariota failing to sustain many drives. He was sacked nine times. Falcons QB Matt Ryan has six picks in three games.
On the spot: Titans WR A.J. Brown. After Adam Humphries and Delanie Walker, Brown got the most targets against Jacksonville, with five. He was taken out of the game by Jalen Ramsey and A.J. Bouye, and needs to be much better to give Mariota more downfield options.
Falcons QB Matt Ryan: Everyone else is doing his part. Ryan can light up the scoreboard, but in a pass-happy league, he must be superb more often than not, and he hasn’t been.
The pick: Falcons 24 Titans 16 3 of 15
LA CHARGERS (1-2) AT MIAMI (0-3), Sunday, 1 p.m. ET
TV: CBS LINE: Los Angeles -16.5
What you need to know: In Week 3,the Chargers couldn’t get to Deshaun Watson like the last several Texans opponents did, and it cost them dearly. Watson made big plays, including a 53-yard touchdown pass on a broken play, to beat Los Angeles. The Chargers have only four sacks, something that must change in a hurry, particularly with safety Derwin James out for at least half the season and the Chiefs already two games ahead in the AFC West. In Week 3, Miami was competitive with Dallas for 30 minutes, but couldn’t take advantage of three first-half red-zone trips. The Dolphins’ pass defense wasn’t gashed by Dak Prescott, but it had no answers for Ezekiel Elliott and Tony Pollard (combined for 228 yards on 32 carries).
On the spot: Chargers DE Melvin Ingram. Ingram has just one sack. Pro Football Focus’ grading is more kind to him, crediting him with six hurries. He must be better to help the Chargers’ so-so secondary.
Dolphins WR Preston Williams: Against Dallas, Williams dropped a perfectly thrown pass from Josh Rosen that would have gone for a touchdown. He finished with a team-leading 12 targets, but only four catches for 68 yards. Williams (6-5, 218) has prototype size for the position, and Rosen will continue to look his way.
The pick: Chargers 30 Dolphins 17 4 of 15
OAKLAND (1-2) AT INDIANAPOLIS (2-1), Sunday, 1 p.m. ET
TV: CBS LINE: Indianapolis -6.5
What you need to know: In Week 3, Oakland made things much too easy for the Vikings. QB Kirk Cousins barely broke a sweat, and RB Dalvin Cook dominated. One of the Raiders’ two scores came on a trick play. In Indy in Week 3, Jacoby Brissett completed his first three passes as the Colts jumped to a 20-3 halftime lead in a win over Atlanta. More good news for Frank Reich’s team: Adam Vinatieri was perfect, including a 49-yard field goal.
On the spot: Raiders RB Josh Jacobs. Oakland needs a complementary piece in the passing game to go with Waller and Tyrell Williams, and Jon Gruden seems to want that piece to be Jacobs. He has been effective as a runner (228 yards), but has only one catch for 28 yards.
Colts S Khari Willis: Malik Hooker will be out roughly a month and a half with a torn meniscus, and the burden of replacing him falls to Willis, a rookie fourth-rounder. Hooker was in the midst of another solid season, so Willis has big shoes to fill.
The pick: Colts 28 Raiders 13 5 of 15
NEW ENGLAND (3-0) AT BUFFALO (3-0), Sunday, 1 p.m. ET
TV: CBS LINE: New England -7
What you need to know: The Pats’ defense still hasn’t allowed a touchdown, as both Jets scores last week came from their defense. New England is scary good on both sides of the ball. The Patriots’ defense is best in the league in points and yards allowed, and their offense is the second highest scoring. The only area where they’ve been even somewhat deficient is rushing offense, but when Tom Brady is running the show, that hardly matters. Josh Allen has been on a roller coaster ride, but he has made enough plays to complement a top-five Bills defense and rally the team to two fourth-quarter, comeback wins.
On the spot: Patriots RB Sony Michel. Michel averages less than 2.5 yards per carry. Although the Pats look unstoppable now, chances are they’ll need Michel soon, certainly in the postseason, if they are going to successfully defend their Super Bowl title.
Bills RB Frank Gore. Devin Singletary’s status is uncertain, so the task of churning out first downs and chewing up clock might fall to the ageless Gore, who has rushed for 164 yards (3.7 a carry).
The pick: Patriots 31 Bills 14 6 of 15
CLEVELAND (1-2) AT BALTIMORE (2-1), Sun., 1 p.m. ET
TV: CBS LINE: Baltimore -7
What you need to know: Cleveland is a mess offensively, and most of it is Baker Mayfield’s fault. The quarterback looks jittery in the pocket, holds the ball too long and runs himself into trouble when standing pat and making a throw would be more prudent. Freddie Kitchens takes much of the blame, but if his QB doesn’t snap out of his funk, the Browns’ hyped season will be on life support a mere quarter of the way in. In Week 3, the Ravens lost in Kansas City, and Lamar Jackson’s play was spotty. The Ravens are good, and certainly better than many thought they would be, but the K.C. loss proved that Jackson is not a finished product and Baltimore needs to do some work defensively.
On the spot: Browns QB Baker Mayfield. He courted the hype, the attention and the haters, and now Mayfield isn’t holding up his end (56.9 completion %, 805 yards passing, 70.3 QB rating).
Ravens S Earl Thomas: With Mayfield holding onto the ball too long, Thomas could have a field day baiting him into traps. That said, his past two games have not been great, per Pro Football Focus grading, so Mayfield may end up going right at him.
The pick: Browns 26 Ravens 23 7 of 15
WASHINGTON (0-3) AT NY GIANTS (1-2), Sunday, 1 p.m. ET
TV: FOX LINE: New York -3
What you need to know: In Week 3, Washington was sloppy, careless and non-competitive at home on MNF against Chicago. Case Keenum was ineffective; coupled with a winless start, that might compel Daniel Snyder to fire Jay Gruden. Or perhaps he will pressure the head coach to start rookie QB Dwayne Haskins. Gruden still thinks the season can be salvaged, so he’s resisting — for now. Speaking of throwing a rookie out there to see what he can do, Daniel Jones made GM Dave Gettleman look brilliant. Jones was a revelation, throwing for two touchdowns and running for two more in his Giants debut, a win over the Bucs. He’s the talk of New York, but now comes the hard part: doing it twice in a row.
On the spot: Redskins QB Case Keenum. Keenum was good in Washington’s first two games, but he struggled against the Bears, throwing three interceptions, one of which was returned for a touchdown. If he doesn’t bounce back, Haskins-mania will reach a fever pitch.
Giants QB Daniel Jones: Jones instantly energized the Giants, and it seemed like he brought pieces of the offense into play that Eli Manning could not. Jones will try to keep the good times rolling without his most dynamic weapon. RB Saquon Barkley is out 4-8 weeks. Your move, Wayne Gallman.
The pick: Giants 24 Redskins 20 8 of 15
CAROLINA (1-2) AT HOUSTON (2-1), Sunday, 1 p.m. ET
TV: FOX LINE: Houston -4
What you need to know: This game figured to be a great matchup when fans thought it would be Cam Newton versus Deshaun Watson, but Newton’s absence might make for an even better shootout. In Week 3, Newton replacement Kyle Allen lit up the Cardinals. Christian McCaffrey backed Allen with 153 yards rushing, and TE Greg Olsen had two touchdown catches. Carolina looked like a different — and much better — team with Allen. In Week 3 against the Chargers, the Texans finally protected Watson, as he was sacked fewer than four times in a game for the first time in eight regular-season contests. He was rarely pressured outside of those two sacks, and made the Chargers pay. Despite taking a beating, Watson still has a 108.6 passer rating.
On the spot: Panthers QB Kyle Allen. Can Allen do it two weeks in a row? Houston’s defense is second best in the NFL. One more star turn by Allen might cause a quarterback controversy in Charlotte.
Texans WR Will Fuller: The slow-starting Fuller doesn’t have a touchdown catch and has only 160 yards receiving through three games. The Texans need a legitimate second option when DeAndre Hopkins is covered, and Fuller is still best-suited for the job.
The pick: Texans 30 Panthers 21 9 of 15
KANSAS CITY (3-0) AT DETROIT (2-0-1), Sunday, 1 p.m. ET
TV: FOX LINE: Kansas City -6
What you need to know: In Week 3, the Chiefs passed their test against Baltimore, and now they get another interesting one in the Lions. Kansas City’s running back situation isn’t ideal, but it feels like it almost doesn’t matter with the way Patrick Mahomes is playing. Incredibly enough, Mahomes is ahead of his 2018 pace for yards passing and TD passes. If he keeps it up, the MVP race will be a formality. Detroit is technically an unbeaten, but its come-from-ahead tie against the Cardinals feels like a loss. Still, the Lions have gutted out a win against the Chargers, and shocked Philadelphia on the road. No one is talking much about Matt Patricia’s team as a threat in the NFC North, but if it wins this game, everyone will be.
On the spot: Chiefs RB Darrel Williams. He rushed for 62 yards on nine carries in Week 3, and figures to get calls again this week. If banged-up LeSean McCoy is limited again, the burden of giving K.C. at least the threat of the run will fall to Williams.
Lions S Tracy Walker: Walker’s Pro Football Focus coverage grade through three weeks is 75.6, which is good to very good. But he’ll need to be fantastic, because if Earl Thomas was targeted by Mahomes and Andy Reid last week, they’ll likely go after Walker this week.
The pick: Chiefs 38 Lions 20 10 of 15
TAMPA BAY (1-2) AT LA RAMS (3-0), Sunday, 4:05 p.m. ET
TV: FOX LINE: Los Angeles -10
What you need to know: Shaq Barrett’s first season as a full-time starter is a smashing success; the linebacker leads the NFL with eight sacks in three games. The Buccaneers’ defense ranks in the top half of the league in yards allowed. It is particularly stingy against the run, giving up only three yards per carry, third best in the league. The Bucs are only 22nd in points allowed, however, owing partly to Jameis Winston, who has thrown two pick-sixes. In Week 3, Cooper Kupp helped the Rams overcome a game defensive effort from the Browns as LA won in Cleveland. Kupp consistently exploited coverage mismatches, and he and Jared Goff were on the same page all game. Kupp leads the Rams in catches (23) and touchdowns (2).
On the spot: Bucs QB Jameis Winston. In Week 3, Winston and Mike Evans finally got going against the Giants, with Evans racking up 190 yards and three touchdowns. If the Bucs steal a win against the Rams, it may help coach Bruce Arians decide if Winston is worth a long-term investment.
Rams WR Cooper Kupp: The Bucs are stingy against the run game, so it might fall again to Kupp to spark the offense. He might be Los Angeles’ best overall receiver; he certainly played like it against the Browns. Tampa’s pass defense is suspect, so Kupp could have a big day.
The pick: Rams 27 Buccaneers 23 11 of 15
SEATTLE (2-1) AT ARIZONA (0-2-1), Sunday, 4:05 p.m. ET
TV: FOX LINE: Seattle -5
What you need to know: Seattle could easily be unbeaten, but sloppy play on special teams, and another fumble by Chris Carson, conspired to cost them in Week 3 against the Saints, who were outgained 515-265. Russell Wilson has been nearly flawless (seven touchdowns and no interceptions). The Seahawks might lean on him even more if Carson’s fumbling problems persist. The Cardinals’ run defense is abysmal. Only two teams in the league are worse — the Bengals and Dolphins. Arizona has yet to hold an opponent under 100 yards on the ground. On the plus side, WR Christian Kirk is developing into a nice weapon for Kyler Murray.
On the spot: Seahawks RB Chris Carson. Pete Carroll gave Carson a vote of confidence, but his three lost fumbles in three games are alarming. He lost only two in his first 18 games as a pro. Rashaad Penny should be back this week, so Carson’s margin for error is minimal.
Cardinals LB Jordan Hicks: Hicks has dropped into coverage more than any other Cardinals linebacker, per Pro Football Focus, but he hasn’t done a good job in that regard. Arizona has been shredded by tight ends each of the first three weeks, and Hicks is part of the issue.
The pick: Seahawks 30 Cardinals 28 12 of 15
MINNESOTA (2-1) AT CHICAGO (2-1), Sunday, 4:25 p.m. ET
TV: CBS LINE: Chicago -2.5
What you need to know: The NFC North may be football’s best division, which means that this battle of 2-1 teams could determine who eventually resides in the cellar. Minnesota is tough to beat when Dalvin Cook is running well; his 375 yards lead the league, as does his 6.6 yards per carry. He’ll have a tough test against a Bears defense that ranks fifth in the league against the run. In Week 3, Chicago got a laugher of a win against Washington, and Mitchell Trubisky finally had an easy, productive night. Much of that was due to Matt Nagy’s play-calling, which consistently had receivers, specifically Taylor Gabriel, running open. Can Chicago sustain that momentum?
On the spot: Vikings FS Harrison Smith. Smith is one of the league’s better safeties, and he’ll have the task of confusing Trubisky and baiting him into risky throws. If he wins the chess match, the Vikings have a good chance to win.
Bears WR Allen Robinson: Gabriel got all the love for his three-touchdown outburst against Washington, but Robinson is Chicago’s best receiving threat. Nagy was able to scheme Gabriel open — he needs to do the same for Robinson.
The pick: Vikings 20 Bears 13 13 of 15
JACKSONVILLE (1-2) AT DENVER (0-3), Sun., 4:25 p.m. ET
By: Chris Mueller